Kamandag is a story about a creature that is half snake and half human. Kamandag begins deep down in a cave called the Ambograw, a place where different sorts of half human and half creature beings called Ambogs live. Its kingdom has six tribes: Hasbaya, snake tribe ruled by Haring Saban (Gardo Versoza); Lobobaya, wolf tribe ruled by Haring Gulag (Zoren Legaspi); Pusbaya, cat tribe ruled by Reyna Kuran (Francine Prieto); Goybaya, monkey tribe ruled by Haring Dinggol (Benjie Paras); Orobaya, bull tribe ruled by Haring Budol (Johnny Delgado) and Rapaya, a long lost reptile tribe ruled by Reyna Ragona (Sunshine Dizon). Haring Saban, who is the King of the half human and half snake people (Hasbaya Tribe) and his regular human wife Alicia (Eula Valdez) (the regular humans in the Ambograw are supposed to be caught and turned into slaves, although Saban fell in love with Alicia) and they had a baby. Though, the baby was destined to be killed because he looked like a regular human instead of an Ambog. Haring Gulag, Saban's enemy and King of Lobobaya Tribe, invited Saban to a battle between the two for the ruler of all Ambograw but Reyna Kuran, queen of Pusbaya Tribe, interfered and set them on fire. Saban died later. Meanwhile, Ikoy (Rainier Castillo) and his sister brought the baby into the human world for his safety. Domeng (Emilio Garcia) and Elena (Melissa Mendez) found a baby and they named him Vergel (Richard Gutierrez). Vergel later discovers his snake powers and his destiny to be a hero. Vergel names himself Kamandag, the savior of all beings. Haring Budol gives Vergel a mysterious bracelet, which was left by his father Haring Saban, and his bracelet makes Vergel transform into his armor. His mission is to bring down all kinds of evil, like his enemies Gulag, Kuran and especially Talim. Lucero (Mark Anthony Fernandez), Vergel's close friend and later enemy, becomes another half-snake half-human and becomes Kamandag's mortal enemy, who names himself as Talim. Kamandag and Talim fights for their love and glory.
Cast and characters
· Richard Gutierrez as Vergel / Kamandag
Ø The son of the Hasbayan King, Vergel is brought to the world of the mortals to escape his fate in Ambog. He is taken in by a kind couple who adopts him as their own, and Vergel grows up to become a compassionate man who decides to use his emerging powers for the good of everyone. Ten years after the defeat of his enemies, he meets Doro, Lily and Jenny. He chooses Jenny, then he actually tries to save Lily from the three kidnappers.
· Mark Anthony Fernandez as Lucero Serrano / Talim
Ø Lucero was initially Vergel's best friend, but because of different upbringing and because they uphold different values, they become mortal enemies. Lucero shares the same powers as Vergel, but he would rather use his for personal gains. He joins Kamandag to save Jenny but he betrays him so Kamandag stabs him. He dies in an explosive blast to sacrifice his life for Jenny and Kamandag.
· Maxene Magalona as Lily
Ø Lily hides a secret love for her childhood best friend: Vergel. She's also the lost daughter of Domeng who impregnated Vivian, her mother. Ten years later, she meets Vergel and she tells him that she's engaged with her fiancee. She gets kidnapped by three men while she watched Vergel and Jenny kissing but he saved her actually in the end.
· Jewel Mische as Jenny
Ø Jenny is a Manila girl who becomes the woman both Vergel and Lucero will fight for. But the city girl hides a secret about her identity. Ten years later, she kisses Vergel but she sees Lily kidnapped by three men so she orders Vergel to save her.
· Ehra Madrigal as Ditas / Denise / Lady Kamandag
Ø Ditas is the real daughter of Domeng and Elena. Vergel treats her as his real sister. She has snake powers which comes from Vergel's blood. She's a rival to Kamandag and Lucero due to their snake powers. She will join Kamandag's forces in the process. She reveals to be Lily's half sister.
· Eula Valdez / Glaiza de Castro (young) as Alicia
Ø Alicia is a mother of Kamandag and wife of King Saban then later King Gulag. She seeks her missing son and her father to reunite with them once again.
· Johnny Delgado as King Budol
Ø King of Orobaya tribe who is King Saban's close friend. Much like Saban, Budol's benevolence towards humanity as well as diplomatic skills are matched only by the beastly brute strength he displays in battle. He will later have his subordinates take the young Vergel into the mortal world where he would be safest from Gulag's reach and then eventually hand over the bracelet once owned by his friend to Vergel in inheritance. He was punished and then executed by his own son Agol and King Gulag.
· Zoren Legaspi as King Gulag
Ø The ruler of the Lobobaya clan, King Gulag nurses a deep hatred for Haring Saban—because of a woman he lost to the rule of the Hasbaya tribe. Like Reyna Kuran, he is cruel to his mortal slaves. He becomes furious and finds vengeance after the death of his son Adlak (Kamandag's half-brother), who was killed by Lily. He is beheaded by Kamandag in the final battle.
· Ariel Rivera as Abdon Serrano
Ø Lucero's father, Abdon is a small-time businessman who makes his business grow through unlawful means. He's also a son of Lolo Pepe and brother of Alicia. His life ends when Ditas bites and poisons him to death.
· Ronaldo Valdez / Ramon Christopher (Young) as Don Pepe
Ø Don Pepe is a rich old man who longs to find his missing daughter. In the end, he reunites with Alicia after his long successful recovery by Eliza.
· Francine Prieto as Reyna Kuran
Ø The most cunning ruler in the land of Ambograw, Queen Kuran leads the pack of the Pusbaya. She is most cruel to her slaves from the mortal world. She is stabbed to death by Alicia and dropped into the molten lava.
· Rainier Castillo as Ikoy
Ø A Goybayan who is one of Kamandag's allies in his fight against evil. He's a friend of Vergel/Kamandag. Dies in the final battle.
· Francis Magundayao as Boyong / Dagok
Ø Another one of Domeng's adopted kids; Boyong also comes from the world of the Ambog. There is not a lot known about his real origins. He's the son of Reynang Ragona. He has fire powers which is inherited by his mother. His real name is Dagok.
· Melissa Mendez as Elena
Ø Ditas' mother who was separated from Domeng. She's also the adoptive mother of Vergel. In the end, Elena repents her sins to Vergel and reunites him with Ditas.
· Benjie Paras as King Dinggol
Ø King of the Goybaya clan, Dinggol is very friendly and very business-minded at the same time. Of all the rulers, he is the only one who doesn't want to be involved in tribal wars and alliances. He is, however, not one who would deliberately just turn his back on a friend especially when they needed him most, as seen when he threw Saban a usable weapon during the final moments of the Snake King's duel against Gulag, and right after Budol's execution - an event that would remain in Dinggol's conscience for some time. He later redeems himself by joining Kamandag's forces to battle King Gulag's forces. In the end, Dinggol is now the king of Ambograw.
· Elvis Gutierrez as Agol
Ø As Haring Budog's son, Agol is a mystery to his people. He's also one of Gulag's allies in punishing slaves. Dies in the final battle.
· Mike "Pekto" Nacua as Doro
Ø Another Ambog adopted by the kindly Domeng and Elena, Doro grows up to become Vergel's sidekick. He can transform himself into a werewolf. Ten years later, he becomes a businessman.
· Gardo Versoza as King Saban
Ø Haring Saban rules of the Hasbaya tribe, and unlike the other rulers, he treats his mortal slaves with the same respect as he would his fellow Hasbayans. Because of this, the humans see him as their only hope in the world of Ambog. He was defeated by his rival Gulag and died in a fire. He finally meets his son in the spirit world and he will help him in the final battle.
· Emilio Garcia as Domeng
Ø Domeng is the kindly man who takes in the abandoned Vergel. He becomes the child's adoptive father and he teaches the orphan the values he will uphold when he becomes of age.
· Sunshine Dizon as Reyna Ragona
Ø Ragona is an Ambog who has fire powers and is the queen of Rapaya Tribe of Abograw. She finally meets her son Boyong/Dagok. She is also one of Kamandag's allies in his fight against King Gulag and Queen Kuran. In the end, Ragona ends up as the queen of Ambograw.
· Renz Valerio as Young Vergel
· Alessandra de Rossi as Eleanor
· Glydel Mercado as Vivian
· Michelle Madrigal as Eliza
· Bryan Revilla as Adlak
· Ram Revilla as Harn
· Maureen Larazabal as Cathy
· Michael Flores as Sahir
· Dominic Roco as Pigo
· Karylle as Spectra
· Alyssa Alano as Reyna Baba
· Ynez Veneracion as Jaime
· Saab Magalona as Eleanor's Friend